Background: The first case of renal transplantation successfully performed in Vietnam was in 1992. So far, there are more than 20 organ transplant centers around the country, having performed approximately 5,255 renal transplantation cases consisting of 5,045 cases from living donors, 205 cases from brain-dead donors, and five cases from donors after circulatory death. Viet Duc Hospital is the top-ranked surgical center in Vietnam and also the highest level hospital in national system of surgical treatment, having performed around 66,355 intensive operations, including 150–200 renal transplantations and 20–30 liver transplantations each year. Therefore, the aim of this study is to describe the outcome of Vietnamese patients receiving renal transplantation derived from brain-dead donors in Viet Duc Hospital over the course of 10 years.
Methods: Cross-sectional descriptive study on 116 patients who have had successful kidney transplantation and are currently being treated at Viet Duc Hospital from May 2010 to May 2020. Various donor and recipient characteristics were analyzed along with graft and patient survival, using Kaplan-Meier method.
Results: The mean age of the recipients was 40.01±12.20 years while that of cadaver was 29.1±10.93 years. Proportion of females among recipients was 40.01%. The most common underlying pathology was chronic glomerulonephritis (81.9%). Tacrolimus-based triple-drug regimen was most commonly. The most common cause of death was sepsis intestinal. More than 80% deaths (4/5) occurred within first 5 years, while acute graft: 4,31%. Cumulative proportion of graft patient survival was 97.4% at 3 years and 96.5% at 5 years. Pretransplant hemodialysis, WIT, HLA mismatch has no significant effect on graft.
Conclusions: Graft and patient survival rate of cadaveric transplant at our center was very well. There is need to sensitize and augment the rate of cadaveric transplantation to increase the donor pool.