Fig. 2. Nomenclature of HLA alleles. Each HLA allele name has a unique number of four fields. The first field describes the allele group, which often corresponds to the serological type. The second field is used to describe the specific HLA protein, and third field provide the information of synonymous mutation within the coding sequence. The fourth field describes the mutations in noncoding regions such as 3’UTR, 5’UTR, and intron. Suffixes may be added to an allele to indicate the expression status of the allele. HLA, human leukocyte antigen. Adapted from Luo et al. Nat Genet 2021;53:1504–16 with permission of Springer Nature [12].
Clin Transplant Res 2024;38:294~308 https://doi.org/10.4285/ctr.24.0055