Comparison of hemodynamic variables between fluid responders and nonresponders at baseline and after fluid challenge
Variable | Fluid responders (n=19) | Fluid nonresponders (n=17) | ||||||
---|---|---|---|---|---|---|---|---|
Baseline-1 (TV, 6 mL/kg) | After TVC (TV, 8 mL/kg) | Baseline-2 (TV, 6 mL/kg) | After fluid challenge (TV, 6 mL/kg) | Baseline-1 (TV, 6 mL/kg) |
After TVC (TV, 8 mL/kg) |
Baseline-2 (TV, 6 mL/kg) |
After fluid challenge (TV, 6 mL/kg) |
|
HR (beats/min) | 89.7±10.5 | 89.9±10.3 | 89.4±10.6 | 81.3±8.0 |
86.2±9.4 | 86.5±9.2 | 86.3±8.9 | 84.5±8.3 |
SAP (mmHg) | 105.8±7.1 | 106.5±7.2 | 106.2±7.0 | 122.3±4.9 |
106.2±6.8 | 106.5±6.2 | 106.8±6.4 | 111.3±7.4 |
DAP (mmHg) | 71.2±4.5 | 71.5±4.8 | 71.4±4.8 | 76.9±4.0 |
70.3±5.2 | 70.3±5.2 | 70.4±5.3 | 71.5±5.8 |
MAP (mmHg) | 82.5±4.9 | 82.7±4.8 | 82.9±4.8 | 92.0±3.7 |
82.2±4.9 | 82.2±4.8 | 82.2±4.9 | 84.6±5.2 |
CVP (mmHg) | 6.89±1.20 | 6.89±1.20 | 6.89±1.20 | 8.42±1.02 |
7.53±0.94 | 7.53±0.94 | 7.53±0.94 | 7.94±0.83 |
SVR (dyne × sec/cm5) | 1,095±139 | 1,091±132 | 1,084±117 | 1,142±110 |
1,102±147 | 1,097±143 | 1,103±134 | 1,131±137 |
CI (L/min/m2) | 5.58±0.51 | 5.61±0.50 |
5.60±0.49 | 5.92±0.44 |
5.47±0.53 | 5.47±0.53 | 5.47±0.53 | 5.44±0.49 |
SVI (mL/m2) | 37.7±5.2 | 38.0±5.3 |
37.8±5.4 | 43.8±5.5 |
41.1±7.3 | 40.9±7.3 | 40.5±7.1 | 41.2±7.4 |
PPV (%) | 8.95±2.39 | 12.26±2.26 |
8.84±2.32 | 6.79±1.40 |
9.18±2.68 | 10.00±2.54 |
9.12±2.47 | 8.24±2.24 |
SVV (%) | 9.04±2.39 | 11.63±2.19 |
8.89±2.26 | 6.63±1.26 |
9.24±2.64 | 9.94±2.46 |
9.35±2.34 | 8.53±2.15 |
Values are presented as mean±standard deviation.
TV, tidal volume; TVC, tidal volume challenge; HR, heart rate; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; MAP, mean arterial pressure; CVP, central venous pressure; SVR, systemic vascular resistance; CI, cardiac index; SVI, stroke volume index; PPV, pulse pressure variation; SVV, stroke volume variation.
a)P<0.05: baseline-1 vs. after fluid challenge; b)P<0.05: baseline-2 vs. after fluid challenge; c)P<0.05: fluid responders vs. fluid nonresponders; d)P<0.05: baseline-1 vs. after TVC.