Fig. 1. Tubular epithelial cell viral cytopathic features in BK virus nephropathy. (A) Ground glass amorphous (arrow) and finely granular (arrowhead) intranuclear inclusions (H&E, ×600). (B) Vesicular intranuclear (arrows) and eosinophilic (arrowhead) intranuclear inclusions (H&E, ×600). (C) Eosinophilic dense granular intranuclear inclusions with circumferential halos (arrows) and necrotic desquamated virally infected tubular cells (arrowheads; Jones methenamine silver, ×600). (D) Different viral cytopathic features (arrows) in one biopsy (PAS, ×400).
