Table. 2.

Center volume and patient outcomes after liver transplantation

Study No. of patients No. of centers Primary outcomes: mortality Cut-off value (case/yr) Impact of case volume
Northup et al. (2006) [16] 9,909 100 90-day mortality Low (≤20)
High (>20)
Insignificant
Salvalaggio et al. (2007) [17] 1,228 86 1-yr mortality
Rate of occurrence of hepatic artery thrombosis
Low (<4)
High (>25)
Significant
Tracy et al. (2009) [18] 34,661 104 The O:E ratio for 1-yr mortality Low (<51)
Medium (51–80)
High (>80)
Change of significance over time
Reese et al. (2009) [19] 3,977 140 1-yr graft failure and 1-yr mortality Low (<51)
Intermediate (51–88)
High (>89)
Insignificant
Ozhathil et al. (2011) [14] 15,668 92–102 Graft and patient survival Low (5–48)
Medium (49–77)
High (78–215)
Significant
Macomber et al. (2012) [15] 5,130 63 Hospital and ICU length of stay, cost and in-hospital mortality Low (11–48)
Medium (48–75)
High (>76)
Significant
Kettelhut et al. (2013) [20] NA 91–106 1-yr and 1-mo mortality rates, 1-yr risk-adjusted mortality Low (<30)
Medium (31–100)
High (>100)
Insignificant
Cheng et al. (2016) [21] 2,938 NA ICU length of stay, hospital stay, postop complication, 1-yr mortality Low (<100)
High (>100)
Significant
Hsieh et al. (2021) [22] 436 1 In-hospital mortality Low (<30)
High (>30)
Significant
Delman et al. (2022) [23] 3,273 110 1-yr mortality Very low (1–2)
Low (3–5)
High (>5)
Significant

O:E, observed-to-expected; ICU, intensive care unit; NA, not available.

Korean J Transplant 2023;37:1~10 https://doi.org/10.4285/kjt.23.0010
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