Table. 3.

Clinical data and characteristics

Variable Protocol biopsy (n=12) Indication biopsy (n=16) Total (n=28) P-value
Patient characteristics
Age (yr) 43.9±14.4 32.9±17.9 37.6±17.1 0.092
Male 8 (66.7) 12 (75.0) 20 (71.4) 0.629
Cause of ESRD 0.671
GN 5 (41.7) 9 (56.2) 14 (50)
Cystic kidney disease 3 (25) 2 (12.5) 5 (17.9)
HTN 0 1 (6.2) 1 (3.6)
Unknown 3 (25) 2 (16.7) 5 (17.9)
Others 1 (8.3) 2 (16.7) 3 (10.7)
Transplantation characteristics
Living donor 8 (66.7) 10 (62.5) 18 (64.3) 0.820
Preoperative desensitization 3 (25.0) 0 3 (10.7) 0.034
ABOi 1 (8.3) 0 1 (3.6) 0.240
Donor age (yr) 44.5±14.4 47.7±9.8 46.4±11.5 0.469
Donor male 6 (50) 8 (50) 14 (50) 1.000
Time to C1q deposition finding from transplantation 0 (0–450) 1,479.5 (6–3,961) 3,961 (0–3,961) <0.001
Follow-up (day) 2,088.0±1,383.4 3,195.6±1,113.4 2,721.0±1,334.2 0.027
Serum creatinine (mg/dL)
At C1q detection 5.3±3.4 1.7±0.5 3.3±2.9 0.008
After 1 year 1.3±0.5 1.7±0.6 1.8±1.6 0.739
After 3 year 1.4±0.9 1.6±0.6 2.2±2.6 0.239
eGFR (mg/min/1.73 m2)
At C1q detection 20.7±18.7 49.1±13.2 37.3±24.7 0.002
After 1 year 57.2±13.7 45.7±10.8 51.9±17.9 0.502
After 3 year 55.4±20.8 45.7±10.8 39.4±15.1 0.062
Urine protein/creatinine ratio
At C1q detection 0.4±0.9 0.7±0.6 0.5±0.6 0.493
After 1 year 0.3±0.7 0.7±0.6 0.5±0.1 0.146
After 3 year 1.0±2.1 0.6±0.6 0.5±0.7 0.938

Values are presented as mean±standard deviation, number (%), or median (range).

ESRD, end-stage renal disease; GN, glomerulonephritis; HTN, hypertension; ABOi, ABO incompatibility; eGFR, estimated glomerular filtration rate.

Korean J Transplant 2022;36:180~186 https://doi.org/10.4285/kjt.22.0032